Pharmaceutical Instruments

Gilson GX-274 ASPEC™ - Automated SPE

GX-274 ASPEC™ - Automated SPE

Maximize efficiency and throughput with the unattended, parallel solid phase extraction processing of samples via Gilson’s GX-274 ASPEC™. It’s as easy as placing your samples on the instrument, inserting SPE cartridges in the mobile racks, and filling solvent reservoirs. Then, create your sample list with the powerful TRILUTION® LH software and press’s that easy.

The GX-274 ASPEC is a higher throughput four-probe instrument capable of processing up to 4 samples in parallel to increase both throughput and the efficiency of your cartridge-based applications. Based on positive pressure elution, this instrument processes up to four samples in a single step with an innovative and proven sealing cap technology, where each cartridge is sealed, run, and monitored individually.
The two 406 Dual Syringe Pumps allow the user to transfer liquids, process up to four samples in parallel, and to monitor pressure on each fluid path individually.

  • Four probe Z-arm increases throughput and efficiency.
  • Positive pressure elution ensures better reproducibility and higher precision.
  • The 406 Dual Syringe Pumps are equipped with independent pressure sensing modules that monitor pressure on each of the four fluid paths and can be used to handle error conditions such as high cartridge pressure or clogged liquid lines.
  • Accommodates 1, 3 and 6 mL SPE cartridges.
  • On-bed reservoirs allow access up to four solvents without taking up a position on the tray.
  • Transfer ports allow access to 2 additional off-bed, large volume solvent reservoirs without taking up any on bed rack positions. Extend this capability through the use of a VALVEMATE® II.
  • Modular design allows the use of Code 200, Code 34x, or Code 37x series racks.
  • Mobile Rack Technology enables use as an SPE instrument as well as a Liquid Handling instrument.
  • Positive pressure elution achieved via Gilson’s sealing cap technology.
  • Eluted product can be fractionated by moving to different collection tubes.
  • SPE process can be performed in either batch or sequential mode to optimize throughput and efficiency.


Liquid Handling Accuracy: >98% (100 μL - 25 mL)
Cartridge capacity: 108 (1 mL), 60 (3 mL), 45 (6 mL)
Sampler Type X/Y/Z with stationary rack design
Probe Positioning Performance Accuracy: ± 0.75 mm in X/Y/Z dimensions
Repeatability: ± 0.20 mm in X/Y/Z dimensions
Arm Speed 350 mm/sec in X dimension
350 mm/sec in Y dimension
125 mm/sec in Z dimension (factory-set at 80 mm/sec)
Vertical Punch Strength 1.4 kg (3.0 lb) per probe
Horizontal Motion Strength X: 2.0 kg (4.5 lb)
Y: 2.0 kg (4.5 lb)
Probe Rinse Probe rinsing and flowing probe rinsing occurs through a dedicated rinse station using up to two flowing outside rinse solvents when integrated with a GX rinse pump
Rack Capacity Up to five Code 20 or 33X/34X Series Racks or five Code 37X Series DEC Racks
Front Panel Two 7-segment blue LED displays and LED indicator lights for power and error messages
Syringe Pump Two 406 Dual Syringe Pumps
Contact Control Two inputs (contact closure control & TTL), two relay outputs, two switched +24V DC 1A outputs and one safety input control
Note: Do not use voltages higher than 30V despite contacts rated for higher voltage
Software Control Computer control via Ethernet communication and TRILUTION® LH Software
Environmental Conditions For indoor use only
Altitude: 2000 m
Temperature: 5ºC - 40ºC
Air pressure: 75 - 105 kPa
Pollution degree: 1 or 2, in accordance with IEC 66
Humidity: Maximum relative humidity 80% for temperatures up to 31º C, decreasing linearly to 50% relative humidity at 40ºC
Manufacturing Standards Meets applicable safety and EMC certification standards; UL and CE certified
Fuse 5 x 20 mm “T” type 2.50A
One for 100 - 120V; two for 220 - 240V
Power Requirement Frequency: 50 - 60 Hz
Voltage: 100 - 240V (universal input)
Current rating: 2.0A for 100 - 120V or 1.0A for 220 - 240V
Power consumption: 250W maximum
Dimensions (w x d x h) 59.7 x 54.1 x 57.1 cm (23.5 x 21.3 x 22.5 in)
Note: This does not include the two 406 Dual Syringe Pumps
Weight 22 kg (48 lb)





Solid Phase Extraction - SPE


Biolab A/S
Sindalsvej 29
8240 Risskkov
Telefon: 86 21 28 66