Clinical/Forensics Instruments

Gilson LC/MS Purification System

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Gilson LC/MS Purification System

Gilson has developed the first easy-to-use, practical mass-based purification system. The  LC/MS Purification System from Gilson features a world class performing MS detector combined with Gilson's industry leading preparative HPLC system to produce a truly unique and usable mass targeted purification system.


Targeted Mass Collection … Simplified!

  • GX Liquid Handling platforms for injection and collection
  • Combine UV/VIS, DAD, ELSD, and MS with TRILUTION LC's powerful conditional logic collection to provide targeted purification
  • Best in class MS performance with large scan range (50 - 3000 amu) and industry leading scan speeds up to 10,000 amu/sec
  • Rugged, easy maintenance source design allows for cleaning without breaking vacuum reducing instrument down time and increasing productivity
  • Integrated syringe pump and calibration vials for compound infusion or tuning removes the need for third party devices
  • Integrated diverter valves allows for automatic switching between infusion or tune flow and the HPLC stream
  • Quick-connect probe allows probes to be easily switched between applications and/or users without breaking vacuum
  • Easily switch between APCI and ESI sources to accommodate reverse phase and normal phase applications

 





















Specifications

Ion Sources

  • Electrospray with pneumatic nebulization assist (flow range up to 1.4 mL/min without splitting)

  • ESI- 0.004 – 1.4 mL/min (no split)

  • Ability to spray from 100% aqueous solutions to 100% organic HPLC solvent
  • Electronically-controlled gas flow rates and temperatures
  • Flow injections analysis, calibration and tuning using the on-board syringe pump or calibration solution vials

  • Vacuum system

  • Four Vacuum Stages Single Quadrupole MS unit with one Turbomolecular (three stage) and one rotary vacuum pump


Operating Conditions

  • Performance Operating Range:    10° - 35°C

  • Safe Operating Range: 5° - 40°C

  • Storage Range: -20° - 60°C

  • Relative Humidity: 25% - 80% (non condensing)


Single Quadrupole Mass Analyzer

  • Mass Range: 50 – 3000 amu

  • Maximum Scan Rate: 10,000 amu/sec

  • Mass Accuracy: ± 0.1 amu/24 hours within ± 3°C change in ambient temperature within the calibrated mass range in scan mode

  • Mass Stability: ± 0.1 amu/12 hours within ±3°C change in ambient temperature


Data Acquisition Modes

  • Full scan

  • Scan with extracted Ion

  • Scan/SIM simultaneously

  • SIM (Selected Ion Monitoring)


Dimensions (w x d x h)

  • 35 x 72.5 x 72 cm (13.7 x 28.5 x 28.5 in.)

  • The ion source extends from the front of the unit an additional 9 cm (3.5 in.)

  • Weight: 240 lbs.


Sensitivity (S/N expressed in the RMS)

  • ESI-SIM: -S/N ≥ 120:1 RMS 1 pg/µLreserpine @ 200 µL/min MeOH/H2O

  • ESI-SIM: -S/N ≥ 100:1 RMS 2 pg/µL
    p-nitrophenol @ 400 µL/min MeOH/H2O

 


Power

  • 230V AC 50/60 Hz, single phase

  • Recommended minimum constant voltage =208

 


Gas Requirements

  • N2 @ 100 psi > 95% pure, hydrocarbon free; Required ~ 20-30 L/min

 


Standard Compliance

  • Single Quadrupole MS Detectors will meet CE and WEEE regulatory standards compliance for the MS unit

 






Produktgruppe

Pharmaceutical

Environmental

Clinical/Forensic

LC-MS Systems

HPLC Systems

Protein Purification systems

Kontakt

Biolab A/S
Sindalsvej 29
8240 Risskkov
Telefon: 86 21 28 66
E-mail: sales@biolab.dk