Pharmaceutical Instruments

Gilson GX-281 Liquid Handler

The GX-281 Liquid Handler




The GX-281 Liquid Handler and autosampler offers unmatched versatility and performance for liquid handling operations including injection, fraction collection and re-injection. The instrument features a revolutionary syringeless solvent delivery system that accommodates various volumes and flow rates. The GX Solvent System features an innovative technology that allows for a large dynamic working range of 2 µL to 100 mL and flow rates of 1 µL/min to 25 mL/min.

  • Revolutionary GX Solvent System on an innovative autosampler: no syringes to replace or change to accommodate different volumes and flow rates; allows for immediate access to up to five solvents and provides a large dynamic volume and flow rate range
  • Continuous flow path design on all injection valves for flow rates up to 200 mL/min: allows system flow to continue even as the injection valve switches from load to inject, ensuring consistent pressure and flow
  • Direct Injection Module features an injection port that is integrated into the valve: removes a source of potential carryover, reduces rinsing times, sample waste and X/Y travel for quicker injection cycle times
  • Enhanced bed capacity over other similar liquid handlers — uses only 33" of linear bench space: holds up to six Code 200 Series Racks with an efficient bed design
  • Separate injection and collection pathways: ensures that fractions are never contaminated from the injection process
  • Jet Wash Rinse system includes a high-flow rinse pump: provides fast and efficient probe cleaning with up to six rinse solvents


Manufacturing Standards Meets applicable safety and EMC certification standards; UL and CE certified
Arm Speed X and Y: 0.01-600.00 mm/sec
Z: 0.01-125.00 mm/sec
Communication Interface RS-232 or GSIOC; Four inputs (contact closure, TTL), four relay outputs, four switched +24V DC 1A outputs, one safety input and one analog input
Liquid Handling† Reproducibility: <2%
Accuracy: ±2% for (100 µL - 25 mL) water
Front Panel ON/OFF and STOP soft keys, LED indicator for power
Horizontal Motion Strength X: 1.4 kg (3 lbs.)
Y: 0.7 kg (1.5 lbs.)
Z: 5.4 kg (12 lbs.)
Injection Carryover <0.005%
Injection Reproducibility <1.0% CV (total loop injection), <3.5% (partial loop injection)
Reservoir Solvents Up to 5
Rinse Solvents Up to 6
Rinse Speed High: 200 rpm
Low: 120 rpm
Bed Capacity Holds up to six Code 200-Series racks
Quantity 576 of 13 mm test tubes
Quantity 450 of 16 mm test tubes
Quantity 420 of 18 mm test tubes
Quantity 180 of 25 mm test tubes
Quantity 62 of 25 or 50 mL scintillation vials
Power Requirements Frequency: 50-60 Hz
Voltage: 100-240V (Universal Input)
Current rating: 5.0A for 100-120V or 2.5A for 220-240V
Power consumption: 500W maximum
Probe Positioning Performance Accuracy: ±0.05 mm in X/Y/Z dimensions
Repeatability: ±0.025 mm in X/Y/Z dimensions
Fraction Collector 3-way Valve 3-port, PTFE, 114 µL internal volume, 10 µL dead volume, up to 200 mL/min
Sampler Type X/Y/Z with stationary rack design
Software Gilson TRILUTION™ Software
Solvent Delivery Dynamic Range* 2 µL to >100 mL
*For volumes below 100 µL, Liquid Handling and Injection specifications may differ from those listed above.
Flow Rate Up to 25 mL/min
Liquid Contact Materials Valcon H, Nitronic 60 (N60), PTFE
Vertical Punch Strength 4.5 kg (10 lbs.)
Display Panel Two lines of 40 alphanumeric characters, vacuum fluorescent display
Weight 68 kg (150 lbs.)
Dimensions 88.9 x 76.2 x 96.5 cm (35 x 30 x 38 in.)






LC-MS Systems

HPLC Systems


Liquid Handlers - Cartesian Robots


Biolab A/S
Sindalsvej 29
8240 Risskkov
Telefon: 86 21 28 66